| Herceptin proven to benefit women with HER2 positive early breast
Herceptin has demonstrated unprecedented efficacy in treating both early and advanced (metastatic) HER2 positive breast cancer. Given on its own as monotherapy as well as in combination with or following standard chemotherapy, Herceptin has been shown to improve response rates, disease-free survival and overall survival while maintaining quality of life in women with HER2 positive breast cancer. Herceptin received approval for use in the European Union for advanced (metastatic) HER2 positive breast cancer in 2000, and for early (adjuvant) HER2 positive breast cancer in 2006. In the advanced (metastatic) setting, Herceptin is approved for use as a first-line therapy in combination with paclitaxel where anthracyclines are unsuitable, as first-line therapy in combination with docetaxel, and as a single agent in third-line therapy.
Pharmacyclics, Inc. Announces Closing of a Private Financing With
Pharmacyclics currently has four drugs in Phase I to Phase III clinical development for cancer. This includes a leading histone deacetylase inhibitor (PCI-24781) for multiple cancers; an inhibitor of Factor VIIa (PCI-27483) targeting pancreatic, gastric, colon and breast cancers; a first in class inhibitor of Bruton's tyrosine kinase (Btk) (PCI-32765) currently in a Phase I clinical trial and targeting B-cell related oncology applications; a Btk inhibitor in advanced preclinical testing (PCI-45261) targeting autoimmune and allergic indications; and an HDAC-8 inhibitor (PCI-34051) for autoimmune and cancer indications. Motexafin gadolinium (MGd) has completed two Phase III trials in patients with brain metastases from non-small-cell lung cancer (NSCLC) and other cancers and is currently in a Phase II trial for glioblastoma.
Crunch an Apple and Bust Breast Cancer
And better yet, the more apples our hairy little friends were given, the more adenocarcinoma tumors, a leading cause of breast cancer, were prevented. "We not only observed that the treated animals had fewer tumours, but the tumours were smaller, less malignant and grew more slowly compared with the tumours in untreated rats," says Professor Rui Hai Liu of Cornell University's Institute for Comparative and Environmental Toxicology. So why apples? Docs say it's because they're full of antioxidants and flavonoids. Flavonoids, also found in dark chocolate, are especially helpful because they're thought to prevent free radicals from wreaking havoc on DNA. So snack on a red one, a green one, or a yellow one daily and keep BC at bay! .
Study: Cancer Tests May Not be So Cut & Dry
The American Cancer Society recommends a mammography every year to test for breast cancer. But at 56 years old, Jeanne Lenzer doesn't want one. "My doctor was quite upset with me when I told her I was declining a mammography, and she actually suggested to me that she couldn't have me as a patient if I wasn't going to help myself." She's spent years scouring medical reports as an investigative reporter and has come to the conclusion that early detection won't help her live any longer. "Everybody has to make their own choice // but for me as a healthy woman without having a family history, I just don't feel it's proven." The thinking goes back to a 2005 study in the journal of the national cancer institute which essentially says that all breast cancers detected from a mammogram aren't equal...
Other News To Note
ExonHit Therapeutics SA, of Paris, said data were published in Lancet Oncology describing the identification of a deregulated cell function in breast cancer through the analysis of alternative RNA splicing. Study data demonstrated that exons are expressed differently in malignant and benign lesions, and alternative transcripts determine the molecular characteristics of breast malignancy. ? Forma Therapeutics Inc., of Cambridge, Mass., signed a collaboration with the Experimental Therapeutics Centre (ETC) of Singapore under which ETC will access Forma's chemistry platform. Financial terms were not disclosed. Earlier this year, Forma received a $25 million Series A financing from Singapore-based Bio*One Capital and the Novartis Option Fund, and the company signed technology deals with Novartis AG, of Basel, Switzerland, and with Cubist Pharmaceuticals Inc., of Lexington, Mass.
Battling breast cancer, 8000 turn out for Estero race and raise $1
Decked out entirely in pink from head to toe, breast cancer survivor and Estero resident Beverly Dwenger was holding a pink rose to go along with a 40-year-old picture of herself with her daughter, also a breast cancer survivor. Dwenger, 73, had a double-mastectomy last June. Her 42-year-old daughter, Jennifer Thurson of Saginaw, Mich., underwent a mastectomy to remove her left breast in December. "It's overwhelming," Dwenger said of the number of people who turned out for Saturday's race. "It lets you know that you're not alone, and it really lifts your heart up. This is the first race like this that I've ever been to, but I'm never going to miss another one for as long as I live." Race committee treasurer Gary Iverson said 380 teams participated in this year's event, up from 270 last year.
Babble Wrap: Breast Cancer Is Linked To Poor Diet And Low Exercise
Breast cancer is linked to the diet that women had when they were young, a new report claims. Telegraph Jobs Plan To Save Lost Generation As Skilled Migration Slashed Julia Gillard is planning a massive program of skills training and Year 12 retention, fearing that the global recession could create a lost generation of young people stuck on dole queues for so long that they become unemployable. The Australian Networks' Unhealthy Habits Children's favourite television shows are also the worst offenders in terms of promoting junk food, research reveals. SMH Grammar Gives The Edge To Primary School Students Students taught grammar in primary school out-perform their peers in national literacy tests, but their advantage is lost once formal teaching of the subject has ceased.
More Than 1000 Attend Medline's "Together We Can Save Lives
They were there to hear award-winning journalist, television producer and author Linda Ellerbee speak about her breast cancer experience. "I'd come if it was at 4:00 a.m.," said Bonnie Vencill, R.N., C.N.O.R., of Southside Regional Medical Center in Petersburg, Va. "This is an awesome event because it shows how, with courage, women tackle cancer. It's very emotional and uplifting to know that even though there are trials and tribulations, you can persevere." The forum was held in conjunction with the start of the Association of periOpertive Registered Nurses' 56th Congress at the Hyatt Regency McCormick Place. Raising breast cancer awareness among nurses is a key goal of Medline's campaign, as it is the leading cause of death for women age 40-55 and the average age of a nurse is 46.
Water turns pink at VictoryLand
Today, VictoryLand turned the waters of its Grand Fountain pink in support of Joy to Life�s Walk of Life, which annually raises money to fight breast cancer. VictoryLand recently assumed the lead sponsorship role of Presenting Sponsor for this year�s Walk of Life, set for April 18. �All of us at VictoryLand are extremely proud to support Joy to Life in its effort to provide vital cancer screening services to so many people including citizens in Macon County,� said Milton McGregor, president of the entertainment complex based in Shorter, Alabama. McGregor noted that a key mission of VictoryLand is to support charities benefiting people in Macon County. VictoryLand contributes thousands to 60 such charities.
Monmouth College water polo will try to set world record
Additionally, the 24-hour game will serve as a fundraiser, with proceeds going to the National Breast Cancer Foundation. "We thought about raising money for the water polo team by having a large event, but we figured we could probably come up with that money on our own," said co-captain Joe Moran. "Since we liked the idea, we thought, why not do something good with the money?" Senior Jim Travnik, a former member of the team, will be joining his friends one last time for event. "My mom was diagnosed with breast cancer a few years ago, so this sounded like a really good fundraiser and it's something I really look forward to participating in," Travnik said. To show their support for the cause, team members will wear special pink plaid suits that feature the pink breast cancer ribbon.
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